6CMW

Crystal structure of zebrafish Phosphatidylinositol-4-phosphate 5- kinase alpha isoform with bound ATP/Ca2+

Replaces:  5C3V

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	polymer	394	44869.3	1	UniProt (Q503I3) Pfam (PF01504)	Danio rerio (Zebrafish)	Phosphatidylinositol-4-phosphate 5-kinase,type I,alpha,a
2	B (A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
3	C, D (A)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Sequence modifications

A: 49 - 431 (UniProt: Q503I3)

PDB	External Database	Details
Met 46	-	initiating methionine
Ala 47	-	expression tag
Ser 48	-	expression tag
Leu 432	-	expression tag
Glu 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44869.3
Non-Polymers*	Number of molecules	3
	Total formula weight	587.3
All*	Total formula weight	45456.6

*Water molecules are not included.