6CMP
Closed structure of inactive SHP2 mutant C459E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 532 | 61030.8 | 2 | UniProt (Q06124) Pfam (PF00017) Pfam (PF00102) In PDB | Homo sapiens (Human) | Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,Shp2,SH-PTP3 |
| 2 | water | water | 18.0 | 763 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 529 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Glu 459 | Cys 459 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 122061.6 | |
| All* | Total formula weight | 122061.6 |
