6CLZ
MT1-MMP HPX domain with Blade 4 Loop Bound to Nanodiscs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Matrix metalloproteinase-14 | polymer | 196 | 23131.3 | 1 | UniProt (P50281) Pfam (PF00045) In PDB | Homo sapiens (Human) | MMP-14,MMP-X1,Membrane-type matrix metalloproteinase 1,MTMMP1,Membrane-type-1 matrix metalloproteinase,MT1MMP |
| 2 | B, C | Apolipoprotein A-I | polymer | 211 | 24912.2 | 2 | UniProt (P02647) Pfam (PF01442) In PDB | Homo sapiens (Human) | ApoA-I,Apolipoprotein A1 |
| 3 | A, B, C | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 218 | Chemie (PX4) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) |
Sequence modifications
B, C: 55 - 265 (UniProt: P02647)
| PDB | External Database | Details |
|---|---|---|
| Pro 99 | - | insertion |
| Tyr 100 | - | insertion |
| Leu 101 | - | insertion |
| Asp 102 | - | insertion |
| Asp 103 | - | insertion |
| Phe 104 | - | insertion |
| Gln 105 | - | insertion |
| Lys 106 | - | insertion |
| Lys 107 | - | insertion |
| Trp 108 | - | insertion |
| Gln 109 | - | insertion |
| Glu 110 | - | insertion |
| Glu 111 | - | insertion |
| Met 112 | - | insertion |
| Glu 113 | - | insertion |
| Leu 114 | - | insertion |
| Tyr 115 | - | insertion |
| Arg 116 | - | insertion |
| Gln 117 | - | insertion |
| Lys 118 | - | insertion |
| Val 119 | - | insertion |
| Glu 120 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 72955.7 | |
| Non-Polymers* | Number of molecules | 220 |
| Total formula weight | 148067.4 | |
| All* | Total formula weight | 221023.0 |
