6CIJ
Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | V(D)J recombination-activating protein 1 | polymer | 776 | 88670.8 | 2 | UniProt (P15919) Pfam (PF00097) Pfam (PF10426) Pfam (PF12940) In PDB | Mus musculus (Mouse) | RAG-1 |
2 | F | DNA (46-MER) | polymer | 46 | 14268.1 | 1 | Homo sapiens | ||
3 | I | DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3') | polymer | 16 | 4880.2 | 1 | Homo sapiens | ||
4 | J | DNA (5'-D(P*CP*TP*GP*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3') | polymer | 20 | 6091.9 | 1 | Homo sapiens | ||
5 | G | DNA (60-MER) | polymer | 61 | 18809.0 | 1 | Homo sapiens | ||
6 | N | High mobility group protein B1 | polymer | 163 | 18897.9 | 1 | UniProt (P09429) Pfam (PF09011) Pfam (PF00505) In PDB | Homo sapiens (Human) | High mobility group protein 1,HMG-1 |
7 | L | DNA (30-MER) | polymer | 30 | 9138.9 | 1 | Homo sapiens | ||
8 | D, B | V(D)J recombination-activating protein 2 | polymer | 520 | 58158.3 | 2 | UniProt (P21784) Pfam (PF03089) Pfam (PF13341) In PDB | Mus musculus (Mouse) | RAG-2 |
9 | M | DNA (41-MER) | polymer | 41 | 12655.2 | 1 | Homo sapiens | ||
10 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
11 | A, C | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
A, C: 265 - 1040 (UniProt: P15919)
D, B: 1 - 520 (UniProt: P21784)
PDB | External Database | Details |
---|---|---|
Gln 962 | Glu 962 | conflict |
PDB | External Database | Details |
---|---|---|
Ala 490 | Thr 490 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 378399.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 211.0 | |
All* | Total formula weight | 378610.4 |