6CG0
Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | V(D)J recombination-activating protein 1 | polymer | 775 | 88523.6 | 2 | UniProt (P15919) Pfam (PF00097) Pfam (PF10426) Pfam (PF12940) In PDB | Mus musculus (Mouse) | RAG-1 |
| 2 | D, B | V(D)J recombination-activating protein 2 | polymer | 520 | 58158.3 | 2 | UniProt (P21784) Pfam (PF03089) Pfam (PF13341) In PDB | Mus musculus (Mouse) | RAG-2 |
| 3 | F | DNA (46-MER) | polymer | 46 | 14268.1 | 1 | Escherichia coli K-12 | ||
| 4 | I | DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3') | polymer | 16 | 4880.2 | 1 | Homo sapiens | ||
| 5 | J | DNA (5'-D(P*CP*TP*GP*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3') | polymer | 19 | 5802.7 | 1 | Escherichia coli K-12 | ||
| 6 | G | DNA (60-MER) | polymer | 60 | 18479.8 | 1 | Escherichia coli K-12 | ||
| 7 | L | DNA (30-MER) | polymer | 30 | 9138.9 | 1 | Escherichia coli K-12 | ||
| 8 | M | DNA (41-MER) | polymer | 41 | 12655.2 | 1 | Escherichia coli K-12 | ||
| 9 | N | High mobility group protein B1 | polymer | 126 | 14604.7 | 1 | UniProt (P09429) Pfam (PF09011) Pfam (PF00505) In PDB | Homo sapiens (Human) | High mobility group protein 1,HMG-1 |
| 10 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 11 | A, C | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
A, C: 265 - 1039 (UniProt: P15919)
D, B: 1 - 520 (UniProt: P21784)
| PDB | External Database | Details |
|---|---|---|
| Gln 962 | Glu 962 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 490 | Thr 490 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 373193.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 211.0 | |
| All* | Total formula weight | 373404.5 |
