6CF7
Crystal structure of the A/Solomon Islands/3/2006(H1N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Hemagglutinin | polymer | 326 | 36423.8 | 1 | UniProt (A7Y8I1) Pfam (PF00509) In PDB | Influenza A virus (A/Solomon Islands/3/2006(H1N1)) | |
| 2 | B | Hemagglutinin | polymer | 174 | 19956.1 | 1 | UniProt (F2NZB4) Pfam (PF00509) In PDB | Influenza A virus (A/Solomon Islands/3/2006(H1N1)) | |
| 3 | C | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | B | N-[2-(2-{4-[(R)-(2-methyl-2H-tetrazol-5-yl)(phenyl)methyl]piperazine-1-carbonyl}pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide | non-polymer | 537.6 | 1 | Chemie (EZ7) | |||
| 8 | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A: 11 - 329 (UniProt: A7Y8I1)
| PDB | External Database | Details |
|---|---|---|
| Arg 53 | Leu 60 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56380.0 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2184.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 758.8 | |
| All* | Total formula weight | 59322.8 |
