6CF5

Crystal structure of the A/Viet Nam/1203/2004(H5N1) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	Hemagglutinin	polymer	334	37948.0	3	UniProt (Q5EP31) Pfam (PF00509) UniProt (by SIFTS) (Q6DQ33) In PDB	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
2	B, D, F	Hemagglutinin	polymer	177	20414.5	3	UniProt (Q6DQ18) Pfam (PF00509) UniProt (by SIFTS) (A8UDR1) In PDB	Influenza A virus (A/Viet Nam/1203/2004(H5N1))
3	G, H, I	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	A, C, E	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID	non-polymer		207.3	3	Chemie (NHE)
5	A, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	A, B, C, D, E	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	9	Chemie (PEG)
7	E, A, C	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
8		water	water		18.0	1328	Chemie (HOH)

Sequence modifications

A, C, E: 11 - 333 (UniProt: Q5EP31)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag

B, D, F: 1 - 174 (UniProt: Q6DQ18)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	175087.6
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	19
	Total formula weight	2608.9
All*	Total formula weight	178969.7

*Water molecules are not included.