6CEX
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin | polymer | 323 | 35506.9 | 3 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 2 | B, D, F (B, D, F) | Hemagglutinin | polymer | 174 | 20041.1 | 3 | UniProt (P03436) Pfam (PF00509) | Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus (strain NT60)) | |
| 3 | G, K (G, K) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 4 | H, I, J, L, M... (H, I, J, L, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | N (N) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | DA, HA, P, V, Y... (E, F, A, B, C) | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 6 | Chemie (NHE) | |||
| 7 | EA, FA, GA, IA, Q... (E, F, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 8 | BA, CA, JA, T, U... (D, F, A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 9 | AA (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 10 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 744 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: Q91MA7)
B, D, F: 1 - 174 (UniProt: P03436)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | Arg 468 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 166644.2 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4630.3 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3681.9 | |
| All* | Total formula weight | 174956.4 |
