6CDQ
Crystal structure of the W202F variant of catalase-peroxidase from B. pseudomallei with INH bound.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Catalase-peroxidase | polymer | 728 | 79498.0 | 2 | UniProt (Q3JNW6) Pfam (PF00141) | Burkholderia pseudomallei (strain 1710b) | CP,Peroxidase/catalase |
| 2 | C, L (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, M (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F, J, O, R (A, B) | OXYGEN MOLECULE | non-polymer | 32.0 | 4 | Chemie (OXY) | |||
| 6 | G, P (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 7 | H, I, Q (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 8 | K, S (A, B) | pyridine-4-carbohydrazide | non-polymer | 137.1 | 2 | Chemie (NIZ) | |||
| 9 | T, U (A, B) | water | water | 18.0 | 1272 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 748 (UniProt: Q3JNW6)
| PDB | External Database | Details |
|---|---|---|
| Phe 202 | Trp 182 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 158995.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2296.6 | |
| All* | Total formula weight | 161292.5 |
