6C9R

Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(thiophen-3-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Adenosine kinase	polymer	337	35980.5	2	UniProt (A5U4N0) Pfam (PF00294) UniProt (by SIFTS) (P9WID5) In PDB	Mycobacterium tuberculosis	AK
2	A, B	9-beta-D-ribofuranosyl-6-(thiophen-3-yl)-9H-purine	non-polymer		334.4	4	Chemie (ERJ)
3	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	276	Chemie (HOH)

Sequence modifications

A, B: 1 - 324 (UniProt: A5U4N0)

PDB	External Database	Details
Gly -12	-	expression tag
Leu -11	-	expression tag
Gln -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71961.0
Non-Polymers*	Number of molecules	7
	Total formula weight	1475.5
All*	Total formula weight	73436.5

*Water molecules are not included.