6C91
Structure of GRP94 with a resorcinylic inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, B) | Endoplasmin | polymer | 236 | 26514.0 | 2 | UniProt (P41148) Pfam (PF13589) | Canis lupus familiaris (Dog) | 94 kDa glucose-regulated protein,GRP-94,Heat shock protein 90 kDa beta member 1 |
| 2 | C, D, I, J, K... (C, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | E, M (C, B) | 5-[2-(1-benzyl-1H-imidazol-2-yl)ethyl]-4,6-dichlorobenzene-1,3-diol | non-polymer | 363.2 | 2 | Chemie (EQD) | |||
| 4 | F, G, H, N, O... (C, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | T, U (C, B) | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
C, B: 69 - 286 (UniProt: P41148)
C, B: 328 - 337 (UniProt: P41148)
| PDB | External Database | Details |
|---|---|---|
| Gly 65 | - | expression tag |
| Ser 66 | - | expression tag |
| His 67 | - | expression tag |
| Met 68 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 287 | - | linker |
| Gly 288 | - | linker |
| Gly 289 | - | linker |
| Gly 290 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53028.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1861.5 | |
| All* | Total formula weight | 54889.5 |
