6C7Q
BRD4 BD2 in complex with compound CE277
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 131 | 15266.6 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A | 7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-2-methyl-N-(1-methyl-1H-indazol-3-yl)-9H-pyrimido[4,5-b]indol-4-amine | non-polymer | 453.5 | 1 | Chemie (EO1) | |||
| 3 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 333 - 460 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 330 | - | expression tag |
| Asn 331 | - | expression tag |
| Ala 332 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15266.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 453.5 | |
| All* | Total formula weight | 15720.0 |
