6C73
Tryptophan synthase Q114A mutant (internal aldimine state) in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) with cesium ion bound in the metal coordination site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan synthase alpha chain | polymer | 268 | 28698.8 | 1 | UniProt (P00929) Pfam (PF00290) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 2 | B (B) | Tryptophan synthase beta chain | polymer | 395 | 42617.5 | 1 | UniProt (P0A2K1) Pfam (PF00291) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 3 | AA, C, D, E, F... (B, A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 20 | Chemie (DMS) | |||
| 4 | L (A) | 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE | non-polymer | 365.2 | 1 | Chemie (F9F) | |||
| 5 | M (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | BA, CA, DA, EA, N (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 7 | FA, GA, HA, O (B, A) | CESIUM ION | non-polymer | 132.9 | 4 | Chemie (CS) | |||
| 8 | P (B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 9 | IA (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 10 | JA, KA (A, B) | water | water | 18.0 | 863 | Chemie (HOH) |
Sequence modifications
B: 2 - 396 (UniProt: P0A2K1)
| PDB | External Database | Details |
|---|---|---|
| Ala 114 | Gln 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71316.3 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 3158.6 | |
| All* | Total formula weight | 74474.8 |
