6C3P
Cryo-EM structure of human KATP bound to ATP and ADP in propeller form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, B, C | ATP-sensitive inward rectifier potassium channel 11 | polymer | 406 | 45144.4 | 4 | UniProt (Q14654) Pfam (PF01007) Pfam (PF17655) In PDB | Homo sapiens (Human) | IKATP,Inward rectifier K(+) channel Kir6.2,Potassium channel,inwardly rectifying subfamily J member 11 |
2 | E, H, G, F | ATP-binding cassette sub-family C member 8 | polymer | 1581 | 177180.2 | 4 | UniProt (Q09428) Pfam (PF00664) Pfam (PF00005) In PDB | Homo sapiens (Human) | Sulfonylurea receptor 1 |
3 | F, A, D, C, E... | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) | |||
4 | E, H, G, F | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
5 | F, E, H, G | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) |
Sequence modifications
A, D, B, C: 1 - 390 (UniProt: Q14654)
PDB | External Database | Details |
---|---|---|
Ser -5 | - | expression tag |
Ala -4 | - | expression tag |
Ser -3 | - | expression tag |
Ala -2 | - | expression tag |
Ser -1 | - | expression tag |
Ala 0 | - | expression tag |
Ser 391 | - | expression tag |
Asn 392 | - | expression tag |
Ser 393 | - | expression tag |
Leu 394 | - | expression tag |
Glu 395 | - | expression tag |
Val 396 | - | expression tag |
Leu 397 | - | expression tag |
Phe 398 | - | expression tag |
Gln 399 | - | expression tag |
Gly 400 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 889298.3 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 5960.7 | |
All* | Total formula weight | 895259.0 |