6C3E
CRYSTAL STRUCTURE OF RIP1 KINASE BOUND TO INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-interacting serine/threonine-protein kinase 1 | polymer | 297 | 33595.8 | 2 | UniProt (Q13546) Pfam (PF07714) | Homo sapiens (Human) | Cell death protein RIP,Receptor-interacting protein 1,RIP-1,Serine/threonine-protein kinase RIP |
| 2 | C, D (A, B) | 2-benzyl-5-nitro-1H-benzimidazole | non-polymer | 253.3 | 2 | Chemie (EJY) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 294 (UniProt: Q13546)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Ala 34 | Cys 34 | conflict |
| Ala 127 | Cys 127 | conflict |
| Ala 233 | Cys 233 | conflict |
| Ala 240 | Cys 240 | conflict |
| Leu 252 | Ile 252 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67191.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 506.5 | |
| All* | Total formula weight | 67698.0 |
