6C14

CryoEM structure of mouse PCDH15-1EC-LHFPL5 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Protocadherin-15	polymer	337	37458.1	2	UniProt (Q99PJ1) Pfam (PF00028)	Mus musculus (Mouse)
2	B, D (B, D)	LHFPL tetraspan subfamily member 5 protein	polymer	228	25067.3	2	UniProt (Q4KL25) Pfam (PF10242)	Mus musculus (Mouse)	Lipoma HMGIC fusion partner-like 5 protein,Tetraspan membrane protein of hair cell stereocilia

Sequence modifications

A, C: 1144 - 1465 (UniProt: Q99PJ1)

PDB	External Database	Details
Gly 1140	-	expression tag
Gln 1141	-	expression tag
Tyr 1142	-	expression tag
Asp 1143	-	expression tag
Thr 1466	-	expression tag
Ala 1467	-	expression tag
Leu 1468	-	expression tag
Phe 1469	-	expression tag
Glu 1470	-	expression tag
Ser 1471	-	expression tag
Arg 1472	-	expression tag
Leu 1473	-	expression tag
Val 1474	-	expression tag
Pro 1475	-	expression tag
Arg 1476	-	expression tag

B, D: 1 - 219 (UniProt: Q4KL25)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Ala -1	-	expression tag
Thr 0	-	expression tag
Phe 220	-	expression tag
Glu 221	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	125050.9
All*	Total formula weight	125050.9

*Water molecules are not included.