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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6BZO

Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)		DNA-directed RNA polymerase subunit alphapolymer34737745.32UniProt (A0A045J8T1)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
UniProt (by SIFTS) (P9WGZ1)		Mycobacterium tuberculosisRNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2C
(C)		DNA-directed RNA polymerase subunit betapolymer1181130198.91UniProt (V9Z879)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
Pfam (PF04560)
UniProt (by SIFTS) (P9WGY9)		Mycobacterium tuberculosisRNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3D
(D)		DNA-directed RNA polymerase subunit beta'polymer1324148074.11UniProt (A0A045J9E2)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
UniProt (by SIFTS) (P9WGY7)		Mycobacterium tuberculosisRNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4E
(E)		DNA-directed RNA polymerase subunit omegapolymer11011777.01UniProt (A0A0T9N9K3)
Pfam (PF01192)
UniProt (by SIFTS) (P9WGY5)		Mycobacterium tuberculosisRNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5F
(F)		RNA polymerase sigma factor SigApolymer53158169.51UniProt (A0A045HD00)
Pfam (PF00140)
Pfam (PF04542)
Pfam (PF04539)
Pfam (PF04545)
UniProt (by SIFTS) (P9WGI1)		Mycobacterium tuberculosis
6G
(J)		RNA polymerase-binding protein RbpApolymer11112993.71UniProt (A0A045IP01)
Pfam (PF13397)
UniProt (by SIFTS) (P9WHJ5)		Mycobacterium tuberculosis
7H
(O)		DNA (32-MER)polymer319565.21Mycobacterium tuberculosis
8I
(P)		DNA (26-MER)polymer267930.21Mycobacterium tuberculosis
9J
(C)		Fidaxomicinnon-polymer1058.01Chemie (FI8)
PubChem (135391138)
PubChem (138107160)
PubChem (138991594)
PubChem (162861841)
PubChem (151383)
PubChem (171137781)
PubChem (118555468)
PubChem (123506604)
PubChem (123816381)
PubChem (6440191)
PubChem (129010003)
PubChem (129010263)
PubChem (129134564)
PubChem (129897224)
PubChem (131668620)
PubChem (9941472)
PubChem (132285157)
PubChem (132472265)
PubChem (132980491)
PubChem (134545906)
PubChem (10034073)
PubChem (11528171)
PubChem (13858643)
PubChem (137650947)
PubChem (15942712)
PubChem (138976139)
PubChem (138977122)
PubChem (20284238)
PubChem (143727492)
PubChem (23305223)
PubChem (154805964)
PubChem (156022379)
PubChem (156610556)
PubChem (44609697)
PubChem (46174142)
PubChem (58871626)
PubChem (58925621)
PubChem (162861840)
PubChem (162861842)
PubChem (164170938)
PubChem (168311742)
PubChem (168311806)
PubChem (168313228)
PubChem (168317457)
PubChem (168317477)
PubChem (59008169)
PubChem (171669603)
PubChem (171705409)
PubChem (59185390)
PubChem (59828307)
PubChem (70678896)
PubChem (71433506)
PubChem (71735471)
PubChem (9963335)
PubChem (75905631)
PubChem (89251739)
PubChem (89818116)
PubChem (90711861)
PubChem (90749848)
PubChem (90770916)
PubChem (90804732)
PubChem (91193162)
PubChem (91363790)
PubChem (91441582)
PubChem (91455983)
PubChem (91885501)
PubChem (101607192)
PubChem (102580518)
PubChem (117590639)
PubChem (57747794)
PubChem (59828312)
PubChem (89818117)
10K, L
(D)		ZINC IONnon-polymer65.42Chemie (ZN)
11M
(D)		MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
12N, O
(C, D)		waterwater18.06Chemie (HOH)
Sequence modifications
C: 7 - 1178 (UniProt: V9Z879)
PDBExternal DatabaseDetails
Leu 1179-expression tag
Ala 1180-expression tag
Arg 1181-expression tag
His 1182-expression tag
Gly 1183-expression tag
Gly 1184-expression tag
Ser 1185-expression tag
Gly 1186-expression tag
Ala 1187-expression tag
D: 1 - 1316 (UniProt: A0A045J9E2)
PDBExternal DatabaseDetails
His 1317-expression tag
His 1318-expression tag
His 1319-expression tag
His 1320-expression tag
His 1321-expression tag
His 1322-expression tag
His 1323-expression tag
His 1324-expression tag
E: 2 - 110 (UniProt: A0A0T9N9K3)
PDBExternal DatabaseDetails
Gly 1-expression tag
F: 1 - 528 (UniProt: A0A045HD00)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight454199.2
Non-Polymers*Number of molecules4
Total formula weight1213.2
All*Total formula weight455412.4
*Water molecules are not included.

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PDB entries from 2026-03-25

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