6BXC

Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 9 (VLR9) bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Toll-like receptor 5b, Variable lymphocyte receptor B chimera	polymer	455	51169.2	2	UniProt (F8W3J5) UniProt (Q4G1L2) Pfam (PF13855) Pfam (PF11921)	Danio rerio (Zebrafish)
2	C, D (D, C)	Variable Lymphocyte Receptor 9 (VLR9)	polymer	178	19287.6	2		Petromyzon marinus (sea lamprey)
3	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	F, G, H (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	I (D)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	J, K, L, M (A, B, D, C)	water	water		18.0	121	Chemie (HOH)

Sequence modifications

A, B: 22 - 390 (UniProt: F8W3J5)

PDB	External Database	Details
Ala 18	-	expression tag
Asp 19	-	expression tag
Pro 20	-	expression tag
Gly 21	-	expression tag

A, B: 391 - 465 (UniProt: Q4G1L2)

PDB	External Database	Details
Ser 466	-	expression tag
Ala 467	-	expression tag
Ser 468	-	expression tag
Leu 469	-	expression tag
Val 470	-	expression tag
Pro 471	-	expression tag
Arg 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	140913.7
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	4
	Total formula weight	725.7
All*	Total formula weight	142063.8

*Water molecules are not included.