6BXB

Crystal structure of an extended b3 integrin P33

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Chimera protein of Integrin beta-3 and Integrin alpha-L	polymer	466	51952.7	2	UniProt (P05106) UniProt (P20701) Pfam (PF17205) Pfam (PF00362) Pfam (PF00092) Pfam (PF18372)	Homo sapiens (Human)	Platelet membrane glycoprotein IIIa,GPIIIa,CD11 antigen-like family member A,Leukocyte adhesion glycoprotein LFA-1 alpha chain,LFA-1A,Leukocyte function-associated molecule 1 alpha chain
2	C (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
3	D, E, I, J, K (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
4	F, G (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	H (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	L, M (A, B)	water	water		18.0	170	Chemie (HOH)

Sequence modifications

A, B: 1 - 109 (UniProt: P05106)

PDB	External Database	Details
Pro 33	Leu 59	conflict

A, B: 110 - 286 (UniProt: P20701)

PDB	External Database	Details
Trp 171	Arg 214	conflict

A, B: 287 - 459 (UniProt: P05106)

PDB	External Database	Details
Thr 460	-	expression tag
Arg 461	-	expression tag
Glu 462	-	expression tag
Leu 463	-	expression tag
Tyr 464	-	expression tag
Phe 465	-	expression tag
Gln 466	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103905.4
Non-Polymers*	Number of molecules	9
	Total formula weight	1354.6
All*	Total formula weight	105260.0

*Water molecules are not included.