6BXA

Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 2 (VLR2) bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Toll-like receptor 5b, Variable lymphocyte receptor B chimera	polymer	455	51169.2	2	UniProt (F8W3J5) UniProt (Q4G1L2) Pfam (PF13855) Pfam (PF11921)	Danio rerio (Zebrafish)
2	C, D (C, D)	Variable Lymphocyte Receptor 2	polymer	209	22688.5	2		Petromyzon marinus (sea lamprey)
3	E, F, G (E, F, G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	H, I, K, L, M (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
5	J, N, O (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	P, Q, R, S (A, B, C, D)	water	water		18.0	339	Chemie (HOH)

Sequence modifications

A, B: 22 - 390 (UniProt: F8W3J5)

PDB	External Database	Details
Ala 18	-	expression tag
Asp 19	-	expression tag
Pro 20	-	expression tag
Gly 21	-	expression tag

A, B: 391 - 465 (UniProt: Q4G1L2)

PDB	External Database	Details
Ser 466	-	expression tag
Ala 467	-	expression tag
Ser 468	-	expression tag
Leu 469	-	expression tag
Val 470	-	expression tag
Pro 471	-	expression tag
Arg 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	147715.5
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1292.2
All*	Total formula weight	150280.9

*Water molecules are not included.