6BUR
Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica complexed with barbituric acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cyanuric acid amidohydrolase | polymer | 363 | 38484.7 | 4 | UniProt (Q2RGM7) Pfam (PF09663) | Moorella thermoacetica ATCC 39073 | CAH, Barbiturase |
| 2 | E, H, J, L (A, B, C, D) | BARBITURIC ACID | non-polymer | 128.1 | 4 | Chemie (BR8) | |||
| 3 | F (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 4 | G, I, K, M (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 406 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 367 (UniProt: Q2RGM7)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| Ala 103 | Gln 103 | engineered mutation |
| Ala 104 | Glu 104 | engineered mutation |
| Ala 107 | Lys 107 | engineered mutation |
| Ile 279 | Leu 279 | engineered mutation |
| Arg 280 | Lys 280 | engineered mutation |
| Ser 281 | Phe 281 | engineered mutation |
| - | Cys 283 | deletion |
| - | Cys 284 | deletion |
| - | Pro 285 | deletion |
| - | Pro 286 | deletion |
| - | Ala 287 | deletion |
| Asp 283 | Glu 288 | engineered mutation |
| Met 290 | Leu 290 | engineered mutation |
| Asp 291 | Ala 291 | engineered mutation |
| Arg 292 | Lys 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 153938.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 774.7 | |
| All* | Total formula weight | 154713.3 |
