6BQ1
Human PI4KIIIa lipid kinase complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4-kinase III alpha (PI4KA) | polymer | 1647 | 173821.4 | 1 | UniProt (P42356) Pfam (PF19274) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (Human) | PtdIns-4-kinase alpha |
| 2 | B, E (B, F) | Tetratricopeptide repeat protein 7B | polymer | 863 | 96460.6 | 2 | UniProt (Q86TV6) Pfam (PF19440) Pfam (PF13181) Pfam (PF12895) Pfam (PF13424) | Homo sapiens (Human) | TPR repeat protein 7B,Tetratricopeptide repeat protein 7-like-1,TPR repeat protein 7-like-1 |
| 3 | C, F (C, G) | Protein FAM126A | polymer | 292 | 32688.5 | 2 | UniProt (Q9BYI3) Pfam (PF09790) | Homo sapiens (Human) | Hyccin |
| 4 | D (E) | Phosphatidylinositol 4-kinase III alpha (PI4KA) | polymer | 1648 | 173906.5 | 1 | UniProt (P42356) Pfam (PF19274) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (Human) | PtdIns-4-kinase alpha |
| 5 | G, H (A, E) | 5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide | non-polymer | 574.6 | 2 | Chemie (E4S) |
Sequence modifications
A: 1 - 476 (PDB: 6BQ1)
A: 932 - 2102 (UniProt: P42356)
B, F: 1 - 843 (UniProt: Q86TV6)
C, G: 2 - 289 (UniProt: Q9BYI3)
E: 1 - 477 (PDB: 6BQ1)
E: 932 - 2102 (UniProt: P42356)
A: 932 - 2102 (UniProt: P42356)
B, F: 1 - 843 (UniProt: Q86TV6)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Tyr -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Val -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Tyr -11 | - | expression tag |
| Ala -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Ile -8 | - | expression tag |
| Ala -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ala -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Leu 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
E: 932 - 2102 (UniProt: P42356)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 606026.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1149.3 | |
| All* | Total formula weight | 607175.4 |
