6BOH
Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, FB (A, FB) | 16S ribosomal RNA | polymer | 1507 | 489561.2 | 2 | GenBank (46197919) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 2 | B, GB (B, GB) | 23S ribosomal RNA | polymer | 2880 | 936785.6 | 2 | GenBank (46197919) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 3 | C, HB (C, HB) | 5S ribosomal RNA | polymer | 120 | 38882.2 | 2 | GenBank (46197919) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 4 | D, IA, IB, NC (D, IA, IB, NC) | tRNA | polymer | 77 | 24846.9 | 4 | Escherichia coli K-12 | ||
| 5 | E, JB (E, JB) | 50S ribosomal protein L2 | polymer | 275 | 30401.4 | 2 | UniProt (Q72I07) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 6 | F, KB (F, KB) | 50S ribosomal protein L3 | polymer | 206 | 22450.2 | 2 | UniProt (Q72I04) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 7 | G, LB (G, LB) | 50S ribosomal protein L4 | polymer | 205 | 22744.3 | 2 | UniProt (Q72I05) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 8 | H, MB (H, MB) | 50S ribosomal protein L5 | polymer | 182 | 21075.6 | 2 | UniProt (Q72I16) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 9 | I, NB (I, NB) | 50S ribosomal protein L6 | polymer | 180 | 19568.9 | 2 | UniProt (Q72I19) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 10 | J, OB (J, OB) | 50S ribosomal protein L9 | polymer | 148 | 16436.2 | 2 | UniProt (Q72GV5) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 11 | K, PB (K, PB) | 50S ribosomal protein L13 | polymer | 140 | 15927.9 | 2 | UniProt (Q72IN1) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 12 | L, QB (L, QB) | 50S ribosomal protein L14 | polymer | 122 | 13309.6 | 2 | UniProt (Q72I14) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 13 | M, RB (M, RB) | 50S ribosomal protein L15 | polymer | 150 | 16319.1 | 2 | UniProt (Q72I23) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 14 | N, SB (N, SB) | 50S ribosomal protein L16 | polymer | 141 | 15977.9 | 2 | UniProt (Q72I11) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 15 | O, TB (O, TB) | 50S ribosomal protein L17 | polymer | 118 | 13750.1 | 2 | UniProt (Q72I33) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 16 | P, UB (P, UB) | 50S ribosomal protein L18 | polymer | 112 | 12639.8 | 2 | UniProt (Q72I20) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 17 | Q, VB (Q, VB) | 50S ribosomal protein L19 | polymer | 146 | 17217.9 | 2 | UniProt (Q72JU9) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 18 | R, WB (R, WB) | 50S ribosomal protein L20 | polymer | 118 | 13779.3 | 2 | UniProt (Q72L76) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 19 | S, XB (S, XB) | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 2 | UniProt (Q72HR2) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 20 | T, YB (T, YB) | 50S ribosomal protein L22 | polymer | 113 | 12808.1 | 2 | UniProt (Q72I09) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 21 | U, ZB (U, ZB) | 50S ribosomal protein L23 | polymer | 96 | 10759.8 | 2 | UniProt (Q72I06) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 22 | AC, V (V, AC) | 50S ribosomal protein L24 | polymer | 110 | 12085.6 | 2 | UniProt (Q72I15) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 23 | BC, W (W, BC) | 50S ribosomal protein L25 | polymer | 206 | 23238.6 | 2 | UniProt (Q72IA7) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | General stress protein CTC |
| 24 | CC, X (X, CC) | 50S ribosomal protein L27 | polymer | 85 | 9529.1 | 2 | UniProt (Q72HR3) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 25 | DC, Y (Y, DC) | 50S ribosomal protein L28 | polymer | 98 | 11032.2 | 2 | UniProt (Q72G84) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 26 | EC, Z (Z, EC) | 50S ribosomal protein L29 | polymer | 72 | 8670.3 | 2 | UniProt (Q72I12) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 27 | AA, FC (AA, FC) | 50S ribosomal protein L30 | polymer | 60 | 6799.1 | 2 | UniProt (Q72I22) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 28 | BA, GC (BA, GC) | 50S ribosomal protein L31 | polymer | 71 | 8300.5 | 2 | UniProt (Q72JR0) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 29 | CA, HC (CA, HC) | 50S ribosomal protein L32 | polymer | 60 | 6734.1 | 2 | UniProt (P62652) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 30 | DA, IC (DA, IC) | 50S ribosomal protein L33 | polymer | 54 | 6632.9 | 2 | UniProt (Q72GW3) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 31 | EA, JC (EA, JC) | 50S ribosomal protein L34 | polymer | 49 | 6132.4 | 2 | UniProt (P80340) Pfam (PF00468) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 32 | FA, KC (FA, KC) | 50S ribosomal protein L35 | polymer | 65 | 7506.2 | 2 | UniProt (Q72L77) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 33 | GA, LC (GA, LC) | 50S ribosomal protein L36 | polymer | 37 | 4435.4 | 2 | UniProt (Q72I28) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 34 | HA, MC (HA, MC) | mRNA | polymer | 27 | 8862.5 | 2 | synthetic construct | ||
| 35 | JA, KA, OC, PC (JA, KA, OC, PC) | Peptide chain release factor 1 | polymer | 365 | 41285.1 | 4 | UniProt (B7MKB3) Pfam (PF03462) Pfam (PF00472) UniProt (by SIFTS) (P0A7I0) | Escherichia coli | RF-1 |
| 36 | LA, QC (LA, QC) | 30S ribosomal protein S2 | polymer | 256 | 29317.7 | 2 | UniProt (P62662) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 37 | MA, RC (MA, RC) | 30S ribosomal protein S3 | polymer | 239 | 26751.1 | 2 | UniProt (P62663) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 38 | NA, SC (NA, SC) | 50S ribosomal protein S4 | polymer | 209 | 24373.4 | 2 | UniProt (P62664) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 39 | OA, TC (OA, TC) | 30S ribosomal protein S5 | polymer | 162 | 17583.4 | 2 | UniProt (P62665) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 40 | PA, UC (PA, UC) | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 2 | UniProt (P62666) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 41 | QA, VC (QA, VC) | 30S ribosomal protein S7 | polymer | 156 | 18051.0 | 2 | UniProt (P62667) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 42 | RA, WC (RA, WC) | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 2 | UniProt (P62668) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 43 | SA, XC (SA, XC) | 30S ribosomal protein S9 | polymer | 128 | 14429.7 | 2 | UniProt (P62669) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 44 | TA, YC (TA, YC) | 30S ribosomal protein S10 | polymer | 105 | 11955.0 | 2 | UniProt (P62653) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 45 | UA, ZC (UA, ZC) | 30S ribosomal protein S11 | polymer | 129 | 13737.9 | 2 | UniProt (P62654) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 46 | AD, VA (VA, AD) | 30S ribosomal protein S12 | polymer | 132 | 14683.5 | 2 | UniProt (P61941) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 47 | BD, WA (WA, BD) | 30S ribosomal protein S13 | polymer | 126 | 14338.9 | 2 | UniProt (P62655) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 48 | CD, XA (XA, CD) | 30S ribosomal protein S14 type Z | polymer | 61 | 7158.7 | 2 | UniProt (P62656) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 49 | DD, YA (YA, DD) | 30S ribosomal protein S15 | polymer | 89 | 10578.4 | 2 | UniProt (P62657) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 50 | ED, ZA (ZA, ED) | 30S ribosomal protein S16 | polymer | 88 | 10410.0 | 2 | UniProt (P62238) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 51 | AB, FD (AB, FD) | 30S ribosomal protein S17 | polymer | 105 | 12324.7 | 2 | UniProt (P62658) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 52 | BB, GD (BB, GD) | 30S ribosomal protein S18 | polymer | 88 | 10258.3 | 2 | UniProt (P62659) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 53 | CB, HD (CB, HD) | 30S ribosomal protein S19 | polymer | 93 | 10605.5 | 2 | UniProt (P62660) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 54 | DB, ID (DB, ID) | 30S ribosomal protein S20 | polymer | 106 | 11722.1 | 2 | UniProt (P62661) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 55 | EB, JD (EB, JD) | 30S ribosomal protein Thx | polymer | 27 | 3350.0 | 2 | UniProt (P62613) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 56 | AAA, AAB, ABA, ABB, ACA... (B, GB, D, M, HB...) | MAGNESIUM ION | non-polymer | 24.3 | 1428 | Chemie (MG) | |||
| 57 | BNA, LK (GB, B) | BLASTICIDIN S | non-polymer | 422.4 | 2 | Chemie (BLS) | |||
| 58 | AFB, EFB, LDA, SEB, TDA... (IC, LC, V, AC, BA...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) |
Sequence modifications
B, GB: 6 - 2897 (GenBank: 46197919)
X, CC: 1 - 85 (UniProt: Q72HR3)
JA, KA, OC, PC: 1 - 357 (UniProt: B7MKB3)
| PDB | External Database | Details |
|---|---|---|
| C 154 | Unk 1534643 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 11 | Lys 11 | conflict |
| PDB | External Database | Details |
|---|---|---|
| - | Asp 302 | deletion |
| - | Arg 303 | deletion |
| - | Ser 304 | deletion |
| Leu 358 | - | expression tag |
| Glu 359 | - | expression tag |
| His 360 | - | expression tag |
| His 361 | - | expression tag |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| His 364 | - | expression tag |
| His 365 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 114 |
| Total formula weight | 4586347.2 | |
| Non-Polymers* | Number of molecules | 1440 |
| Total formula weight | 36206.5 | |
| All* | Total formula weight | 4622553.7 |
