6BOH
Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, FB (A, FB) | 16S ribosomal RNA | polymer | 1507 | 489561.2 | 2 | GenBank (46197919) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 2 | B, GB (B, GB) | 23S ribosomal RNA | polymer | 2880 | 936785.6 | 2 | GenBank (46197919) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 3 | C, HB (C, HB) | 5S ribosomal RNA | polymer | 120 | 38882.2 | 2 | GenBank (46197919) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 4 | D, IA, IB, NC (D, IA, IB, NC) | tRNA | polymer | 77 | 24846.9 | 4 | Escherichia coli K-12 | ||
| 5 | E, JB (E, JB) | 50S ribosomal protein L2 | polymer | 275 | 30401.4 | 2 | UniProt (Q72I07) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 6 | F, KB (F, KB) | 50S ribosomal protein L3 | polymer | 206 | 22450.2 | 2 | UniProt (Q72I04) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 7 | G, LB (G, LB) | 50S ribosomal protein L4 | polymer | 205 | 22744.3 | 2 | UniProt (Q72I05) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 8 | H, MB (H, MB) | 50S ribosomal protein L5 | polymer | 182 | 21075.6 | 2 | UniProt (Q72I16) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 9 | I, NB (I, NB) | 50S ribosomal protein L6 | polymer | 180 | 19568.9 | 2 | UniProt (Q72I19) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 10 | J, OB (J, OB) | 50S ribosomal protein L9 | polymer | 148 | 16436.2 | 2 | UniProt (Q72GV5) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 11 | K, PB (K, PB) | 50S ribosomal protein L13 | polymer | 140 | 15927.9 | 2 | UniProt (Q72IN1) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 12 | L, QB (L, QB) | 50S ribosomal protein L14 | polymer | 122 | 13309.6 | 2 | UniProt (Q72I14) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 13 | M, RB (M, RB) | 50S ribosomal protein L15 | polymer | 150 | 16319.1 | 2 | UniProt (Q72I23) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 14 | N, SB (N, SB) | 50S ribosomal protein L16 | polymer | 141 | 15977.9 | 2 | UniProt (Q72I11) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 15 | O, TB (O, TB) | 50S ribosomal protein L17 | polymer | 118 | 13750.1 | 2 | UniProt (Q72I33) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 16 | P, UB (P, UB) | 50S ribosomal protein L18 | polymer | 112 | 12639.8 | 2 | UniProt (Q72I20) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 17 | Q, VB (Q, VB) | 50S ribosomal protein L19 | polymer | 146 | 17217.9 | 2 | UniProt (Q72JU9) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 18 | R, WB (R, WB) | 50S ribosomal protein L20 | polymer | 118 | 13779.3 | 2 | UniProt (Q72L76) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 19 | S, XB (S, XB) | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 2 | UniProt (Q72HR2) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 20 | T, YB (T, YB) | 50S ribosomal protein L22 | polymer | 113 | 12808.1 | 2 | UniProt (Q72I09) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 21 | U, ZB (U, ZB) | 50S ribosomal protein L23 | polymer | 96 | 10759.8 | 2 | UniProt (Q72I06) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 22 | AC, V (V, AC) | 50S ribosomal protein L24 | polymer | 110 | 12085.6 | 2 | UniProt (Q72I15) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 23 | BC, W (W, BC) | 50S ribosomal protein L25 | polymer | 206 | 23238.6 | 2 | UniProt (Q72IA7) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | General stress protein CTC |
| 24 | CC, X (X, CC) | 50S ribosomal protein L27 | polymer | 85 | 9529.1 | 2 | UniProt (Q72HR3) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 25 | DC, Y (Y, DC) | 50S ribosomal protein L28 | polymer | 98 | 11032.2 | 2 | UniProt (Q72G84) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 26 | EC, Z (Z, EC) | 50S ribosomal protein L29 | polymer | 72 | 8670.3 | 2 | UniProt (Q72I12) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 27 | AA, FC (AA, FC) | 50S ribosomal protein L30 | polymer | 60 | 6799.1 | 2 | UniProt (Q72I22) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 28 | BA, GC (BA, GC) | 50S ribosomal protein L31 | polymer | 71 | 8300.5 | 2 | UniProt (Q72JR0) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 29 | CA, HC (CA, HC) | 50S ribosomal protein L32 | polymer | 60 | 6734.1 | 2 | UniProt (P62652) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 30 | DA, IC (DA, IC) | 50S ribosomal protein L33 | polymer | 54 | 6632.9 | 2 | UniProt (Q72GW3) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 31 | EA, JC (EA, JC) | 50S ribosomal protein L34 | polymer | 49 | 6132.4 | 2 | UniProt (P80340) Pfam (PF00468) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 32 | FA, KC (FA, KC) | 50S ribosomal protein L35 | polymer | 65 | 7506.2 | 2 | UniProt (Q72L77) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 33 | GA, LC (GA, LC) | 50S ribosomal protein L36 | polymer | 37 | 4435.4 | 2 | UniProt (Q72I28) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 34 | HA, MC (HA, MC) | mRNA | polymer | 27 | 8862.5 | 2 | synthetic construct | ||
| 35 | JA, KA, OC, PC (JA, KA, OC, PC) | Peptide chain release factor 1 | polymer | 365 | 41285.1 | 4 | UniProt (B7MKB3) Pfam (PF03462) Pfam (PF00472) UniProt (by SIFTS) (P0A7I0) | Escherichia coli | RF-1 |
| 36 | LA, QC (LA, QC) | 30S ribosomal protein S2 | polymer | 256 | 29317.7 | 2 | UniProt (P62662) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 37 | MA, RC (MA, RC) | 30S ribosomal protein S3 | polymer | 239 | 26751.1 | 2 | UniProt (P62663) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 38 | NA, SC (NA, SC) | 50S ribosomal protein S4 | polymer | 209 | 24373.4 | 2 | UniProt (P62664) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 39 | OA, TC (OA, TC) | 30S ribosomal protein S5 | polymer | 162 | 17583.4 | 2 | UniProt (P62665) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 40 | PA, UC (PA, UC) | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 2 | UniProt (P62666) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 41 | QA, VC (QA, VC) | 30S ribosomal protein S7 | polymer | 156 | 18051.0 | 2 | UniProt (P62667) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 42 | RA, WC (RA, WC) | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 2 | UniProt (P62668) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 43 | SA, XC (SA, XC) | 30S ribosomal protein S9 | polymer | 128 | 14429.7 | 2 | UniProt (P62669) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 44 | TA, YC (TA, YC) | 30S ribosomal protein S10 | polymer | 105 | 11955.0 | 2 | UniProt (P62653) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 45 | UA, ZC (UA, ZC) | 30S ribosomal protein S11 | polymer | 129 | 13737.9 | 2 | UniProt (P62654) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 46 | AD, VA (VA, AD) | 30S ribosomal protein S12 | polymer | 132 | 14683.5 | 2 | UniProt (P61941) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 47 | BD, WA (WA, BD) | 30S ribosomal protein S13 | polymer | 126 | 14338.9 | 2 | UniProt (P62655) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 48 | CD, XA (XA, CD) | 30S ribosomal protein S14 type Z | polymer | 61 | 7158.7 | 2 | UniProt (P62656) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 49 | DD, YA (YA, DD) | 30S ribosomal protein S15 | polymer | 89 | 10578.4 | 2 | UniProt (P62657) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 50 | ED, ZA (ZA, ED) | 30S ribosomal protein S16 | polymer | 88 | 10410.0 | 2 | UniProt (P62238) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 51 | AB, FD (AB, FD) | 30S ribosomal protein S17 | polymer | 105 | 12324.7 | 2 | UniProt (P62658) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 52 | BB, GD (BB, GD) | 30S ribosomal protein S18 | polymer | 88 | 10258.3 | 2 | UniProt (P62659) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 53 | CB, HD (CB, HD) | 30S ribosomal protein S19 | polymer | 93 | 10605.5 | 2 | UniProt (P62660) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 54 | DB, ID (DB, ID) | 30S ribosomal protein S20 | polymer | 106 | 11722.1 | 2 | UniProt (P62661) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 55 | EB, JD (EB, JD) | 30S ribosomal protein Thx | polymer | 27 | 3350.0 | 2 | UniProt (P62613) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 56 | AAA, AAB, ABA, ABB, ACA... (B, GB, D, M, HB...) | MAGNESIUM ION | non-polymer | 24.3 | 1428 | Chemie (MG) PubChem (888) | |||
| 57 | BNA, LK (GB, B) | BLASTICIDIN S | non-polymer | 422.4 | 2 | Chemie (BLS) PubChem (16667710) PubChem (16758236) PubChem (16760316) PubChem (16760318) PubChem (18772420) PubChem (21124837) PubChem (258) PubChem (23818608) PubChem (25078184) PubChem (16380) PubChem (44119963) PubChem (170012) PubChem (439625) PubChem (5352011) PubChem (5745696) PubChem (124080961) PubChem (124351418) PubChem (12300172) PubChem (124918591) PubChem (132285147) PubChem (138107250) PubChem (162939623) PubChem (16211310) | |||
| 58 | AFB, EFB, LDA, SEB, TDA... (IC, LC, V, AC, BA...) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) |
Sequence modifications
B, GB: 6 - 2897 (GenBank: 46197919)
X, CC: 1 - 85 (UniProt: Q72HR3)
JA, KA, OC, PC: 1 - 357 (UniProt: B7MKB3)
| PDB | External Database | Details |
|---|---|---|
| C 154 | Unk 1534643 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 11 | Lys 11 | conflict |
| PDB | External Database | Details |
|---|---|---|
| - | Asp 302 | deletion |
| - | Arg 303 | deletion |
| - | Ser 304 | deletion |
| Leu 358 | - | expression tag |
| Glu 359 | - | expression tag |
| His 360 | - | expression tag |
| His 361 | - | expression tag |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| His 364 | - | expression tag |
| His 365 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 114 |
| Total formula weight | 4586347.2 | |
| Non-Polymers* | Number of molecules | 1440 |
| Total formula weight | 36206.5 | |
| All* | Total formula weight | 4622553.7 |
