6BO4

Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, D, B, C)	Transient receptor potential cation channel subfamily V member 2	polymer	699	79999.4	4	UniProt (Q9WUD2) Pfam (PF12796) Pfam (PF00520)	Rattus norvegicus (Rat)	TrpV2,Osm-9-like TRP channel 2,OTRPC2,Stretch-activated channel 2B,Vanilloid receptor-like protein 1,VRL-1

Sequence modifications

A, D, B, C: 72 - 726 (UniProt: Q9WUD2)

PDB	External Database	Details
Met 41	-	expression tag
Val 42	-	expression tag
Ser 43	-	expression tag
Ala 44	-	expression tag
Asn 45	-	expression tag
Gly 46	-	expression tag
Asp 47	-	expression tag
Leu 48	-	expression tag
His 49	-	expression tag
Leu 50	-	expression tag
Pro 51	-	expression tag
Ile 52	-	expression tag
Ser 53	-	expression tag
Asn 54	-	expression tag
Glu 55	-	expression tag
Gln 56	-	expression tag
Cys 57	-	expression tag
Met 58	-	expression tag
Pro 59	-	expression tag
Glu 60	-	expression tag
Asn 61	-	expression tag
Asn 62	-	expression tag
Gly 63	-	expression tag
Ser 64	-	expression tag
Leu 65	-	expression tag
Gly 66	-	expression tag
Phe 67	-	expression tag
Glu 68	-	expression tag
Ala 69	-	expression tag
Pro 70	-	expression tag
Thr 71	-	expression tag
Pro 151	Leu 151	conflict
Thr 727	-	expression tag
Glu 728	-	expression tag
Thr 729	-	expression tag
Ser 730	-	expression tag
Gln 731	-	expression tag
Val 732	-	expression tag
Ala 733	-	expression tag
Pro 734	-	expression tag
Ala 735	-	expression tag
Ser 736	-	expression tag
Thr 737	-	expression tag
Pyl 738	-	expression tag
Pro 739	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	319997.7
All*	Total formula weight	319997.7

*Water molecules are not included.