6BM0

Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cleavage and polyadenylation specificity factor subunit 1	polymer	1443	161074.2	1	UniProt (Q10570) Pfam (PF10433) Pfam (PF03178) In PDB	Homo sapiens (Human)	Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit
2	B	pre-mRNA 3' end processing protein WDR33	polymer	587	67546.8	1	UniProt (Q9C0J8) Pfam (PF00400) In PDB	Homo sapiens (Human)	WD repeat-containing protein 33, WD repeat-containing protein WDC146

Sequence modifications

B: 1 - 572 (UniProt: Q9C0J8)

PDB	External Database	Details
Met -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ser -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Leu -1	-	expression tag
Val 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	228621.0
All*	Total formula weight	228621.0

*Water molecules are not included.