6BLR

Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	IAg7 alpha chain	polymer	183	20896.4	1	UniProt (P04228) Pfam (PF00993) Pfam (PF07654)	Mus musculus (Mouse)
2	B (B)	H2-Ab1 protein	polymer	221	25362.3	1	UniProt (Q31135) Pfam (PF00969) Pfam (PF07654)	Mus musculus (Mouse)
3	C (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	D, E (A, B)	water	water		18.0	340	Chemie (HOH)

Sequence modifications

A: 1 - 183 (UniProt: P04228)

PDB	External Database	Details
Cys 64	Asn 89	engineered mutation

B: 4 - 191 (UniProt: Q31135)

PDB	External Database	Details
His -28	-	see remark 999
Leu -27	-	see remark 999
Val -26	-	see remark 999
Glu -25	-	see remark 999
Arg -24	-	see remark 999
Leu -23	-	see remark 999
Tyr -22	-	see remark 999
Leu -21	-	see remark 999
Val -20	-	see remark 999
Cys -19	-	see remark 999
Gly -18	-	see remark 999
Glu -17	-	see remark 999
Glu -16	-	see remark 999
Gly -15	-	linker
Ala -14	-	linker
Gly -13	-	linker
Gly -12	-	linker
Gly -11	-	linker
Ser -10	-	linker
Leu -9	-	linker
Val -8	-	linker
Gly -7	-	linker
Gly -1	-	linker
Ser 0	-	linker
Gly 1	-	linker
Gly 2	-	linker
Gly 3	-	linker
Gly 192	-	expression tag
Gly 193	-	expression tag
Leu 194	-	expression tag
Val 195	-	expression tag
Pro 196	-	expression tag
Arg 197	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46258.7
Non-Polymers*	Number of molecules	1
	Total formula weight	62.1
All*	Total formula weight	46320.8

*Water molecules are not included.