6BL3
Crystal Complex of Cyclooxygenase-2 with indomethacin-butyldiamine-dansyl conjugate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Prostaglandin G/H synthase 2 | polymer | 587 | 67332.7 | 4 | UniProt (Q05769) Pfam (PF00008) Pfam (PF03098) | Mus musculus (Mouse) | Cyclooxygenase-2,COX-2,Glucocorticoid-regulated inflammatory cyclooxygenase,Gripghs,Macrophage activation-associated marker protein P71/73,PES-2,PHS II,Prostaglandin H2 synthase 2,PGHS-2,Prostaglandin-endoperoxide synthase 2,TIS10 protein |
| 2 | E, F, G, H (E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | AA, I, J, O, P... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 4 | BA, K, Q, V (D, A, B, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 5 | CA, L, R, W (D, A, B, C) | 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)butyl]acetamide | non-polymer | 661.2 | 4 | Chemie (L7M) | |||
| 6 | DA, M, N, S, X... (D, A, B, C) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 6 | Chemie (BOG) | |||
| 7 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 856 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 269330.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 8634.7 | |
| All* | Total formula weight | 279663.1 |
