6BKF
Lysyl-adenylate form of human LigIV catalytic domain with bound DNA substrate in open conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA ligase 4 | polymer | 621 | 70695.6 | 1 | UniProt (P49917) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Homo sapiens (Human) | DNA ligase IV,Polydeoxyribonucleotide synthase [ATP] 4 |
| 2 | B (P) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3') | polymer | 11 | 3365.2 | 1 | synthetic construct | ||
| 3 | C (T) | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 18 | 5486.6 | 1 | synthetic construct | ||
| 4 | D (D) | DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3') | polymer | 7 | 2138.4 | 1 | synthetic construct | ||
| 5 | E (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (1549371) PubChem (92144436) PubChem (224) PubChem (12358354) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (122197642) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 6 | F (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 1 - 620 (UniProt: P49917)
| PDB | External Database | Details |
|---|---|---|
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 81685.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 82033.0 |
