6BIZ

HLA-DRB1 in complex with citrullinated Histone 2B peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HLA class II histocompatibility antigen, DR alpha chain	polymer	189	21919.6	1	UniProt (P01903) Pfam (PF00993) Pfam (PF07654)	Homo sapiens (Human)	MHC class II antigen DRA
2	B (B)	HLA class II DR-beta (HLA-DR B)	polymer	200	23294.7	1	UniProt (Q29890) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911)	Homo sapiens (Human)
3	C (C)	Histone2B_73,81cit68-82	polymer	15	1693.8	1	UniProt (by SIFTS) (Q8N257)	Homo sapiens
4	D, E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	F (B)	2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		282.3	1	Chemie (B3P)
6	G, H, I (A, B, C)	water	water		18.0	222	Chemie (HOH)

Sequence modifications

A: 1 - 181 (UniProt: P01903)

PDB	External Database	Details
Thr 182	-	expression tag
Ser 183	-	expression tag
Gly 184	-	expression tag
Asp 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Lys 189	-	expression tag

B: 1 - 190 (UniProt: Q29890)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Thr 191	-	expression tag
Gly 192	-	expression tag
Gly 193	-	expression tag
Asp 194	-	expression tag
Asp 195	-	expression tag
Asp 196	-	expression tag
Asp 197	-	expression tag
Lys 198	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	46908.1
Non-Polymers*	Number of molecules	3
	Total formula weight	724.8
All*	Total formula weight	47632.9

*Water molecules are not included.