6BH9
Caspase-3 Mutant - T152A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Caspase-3 | polymer | 175 | 19729.3 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 2 | C, E | Caspase-3 | polymer | 103 | 12023.8 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 3 | D, G | Ac-Asp-Glu-Val-Asp-CMK | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | Homo sapiens | |
| 4 | A, C, B, E | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 175 (UniProt: P42574)
C, E: 176 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 152 | Thr 152 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Leu 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 64576.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 185.9 | |
| All* | Total formula weight | 64761.9 |
