6BGQ
Caspase-3 Mutant - S150D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Caspase-3 | polymer | 175 | 19787.4 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 2 | B, D (B, D) | Caspase-3 | polymer | 103 | 12048.8 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 3 | E, F (K, L) | Ac-Asp-Glu-Val-Asp-CMK | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | Homo sapiens | |
| 4 | G, M (A, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | H, I, J, K, L... (A, B, C, D) | AZIDE ION | non-polymer | 42.0 | 10 | Chemie (AZI) | |||
| 6 | R (D) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | T, U, V, W, X... (A, B, C, D, K...) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 175 (UniProt: P42574)
B, D: 176 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Asp 150 | Ser 150 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 64742.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 514.1 | |
| All* | Total formula weight | 65256.2 |
