6BGQ

Caspase-3 Mutant - S150D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Caspase-3	polymer	175	19787.4	2	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
2	B, D	Caspase-3	polymer	103	12048.8	2	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
3	K, L	Ac-Asp-Glu-Val-Asp-CMK	polymer	6	534.9	2	BIRD (PRD_000238)	Homo sapiens
4	A, C	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	A, B, C, D	AZIDE ION	non-polymer		42.0	10	Chemie (AZI)
6	D	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7		water	water		18.0	326	Chemie (HOH)

Sequence modifications

A, C: 1 - 175 (UniProt: P42574)

PDB	External Database	Details
Asp 150	Ser 150	engineered mutation

B, D: 176 - 277 (UniProt: P42574)

PDB	External Database	Details
His 278	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	64742.1
Non-Polymers*	Number of molecules	13
	Total formula weight	514.1
All*	Total formula weight	65256.2

*Water molecules are not included.