6BGQ
Caspase-3 Mutant - S150D
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Caspase-3 | polymer | 175 | 19787.4 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
2 | B, D | Caspase-3 | polymer | 103 | 12048.8 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
3 | K, L | Ac-Asp-Glu-Val-Asp-CMK | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | Homo sapiens | |
4 | A, C | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | A, B, C, D | AZIDE ION | non-polymer | 42.0 | 10 | Chemie (AZI) | |||
6 | D | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
7 | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 175 (UniProt: P42574)
B, D: 176 - 277 (UniProt: P42574)
PDB | External Database | Details |
---|---|---|
Asp 150 | Ser 150 | engineered mutation |
PDB | External Database | Details |
---|---|---|
His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 64742.1 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 514.1 | |
All* | Total formula weight | 65256.2 |