6BGK

Caspase-3 Mutant- D9A,D28A,T152D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Caspase-3	polymer	175	19685.3	2	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
2	C, D	Caspase-3	polymer	103	12048.8	2	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
3	F, H	ACE-ASP-GLU-VAL-ASP-0QE	polymer	6	534.9	2	BIRD (PRD_000238)	Homo sapiens
4	A, B, D	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
5	C, D	AZIDE ION	non-polymer		42.0	2	Chemie (AZI)
6	B	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
7		water	water		18.0	522	Chemie (HOH)

Sequence modifications

A, B: 1 - 175 (UniProt: P42574)

PDB	External Database	Details
Ala 9	Asp 9	engineered mutation
Ala 28	Asp 28	engineered mutation
Asp 152	Thr 152	engineered mutation

C, D: 176 - 277 (UniProt: P42574)

PDB	External Database	Details
His 278	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	64538.0
Non-Polymers*	Number of molecules	9
	Total formula weight	294.8
All*	Total formula weight	64832.8

*Water molecules are not included.