6BGA
2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | H-2 class II histocompatibility antigen, E-K alpha chain | polymer | 204 | 23618.5 | 1 | UniProt (P04224) Pfam (PF00993) Pfam (PF07654) | Mus musculus (Mouse) | |
| 2 | B (B) | 2B4 peptide,MHC I-Ek B chain | polymer | 233 | 26586.6 | 1 | UniProt (Q31163) Pfam (PF00969) Pfam (PF07654) | Mus musculus | |
| 3 | C (C) | T cell receptor 2B4 alpha chain | polymer | 220 | 24104.5 | 1 | Mus musculus | ||
| 4 | D (D) | T cell receptor 2B4 beta chain | polymer | 255 | 29007.5 | 1 | Mus musculus | ||
| 5 | E (E) | Velcro peptide | polymer | 15 | 1308.4 | 1 | synthetic construct | ||
| 6 | F, G (F, G) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 7 | H, I (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | J, K, L (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 9 | M (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 10 | N, O, P, Q, R (A, B, C, D, E) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence modifications
A: 1 - 191 (UniProt: P04224)
B: -24 - 2 (PDB: 6BGA)
B: 3 - 198 (UniProt: Q31163)
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 192 | - | expression tag |
| Arg 193 | - | expression tag |
| Gly 194 | - | expression tag |
| Gly 195 | - | expression tag |
| Leu 196 | - | expression tag |
| Glu 197 | - | expression tag |
| Val 198 | - | expression tag |
| Leu 199 | - | expression tag |
| Phe 200 | - | expression tag |
| Gln 201 | - | expression tag |
B: 3 - 198 (UniProt: Q31163)
| PDB | External Database | Details |
|---|---|---|
| Ser 199 | - | expression tag |
| Arg 200 | - | expression tag |
| Gly 201 | - | expression tag |
| Gly 202 | - | expression tag |
| Leu 203 | - | expression tag |
| Glu 204 | - | expression tag |
| Val 205 | - | expression tag |
| Leu 206 | - | expression tag |
| Phe 207 | - | expression tag |
| Gln 208 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 104625.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 734.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 723.6 | |
| All* | Total formula weight | 106083.7 |
