6BFU
Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Spike protein | polymer | 1024 | 112514.8 | 3 | UniProt (A0A140ES81) Pfam (PF01600) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (A0A140ESF1) In PDB | Porcine deltacoronavirus | spike glycoprotein |
| 2 | b, D, d, F, f... | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 9 | In PDB GlyTouCan (G56014GC) | |||
| 3 | a, E, e, H, h... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 21 | In PDB GlyTouCan (G15407YE) | |||
| 4 | c, G, g, P, p... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, i, V | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 6 | B, C, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
A, B, C: 19 - 1021 (UniProt: A0A140ES81)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Cys 1 | - | expression tag |
| Ile 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Val 6 | - | expression tag |
| Val 7 | - | expression tag |
| Ala 8 | - | expression tag |
| Phe 9 | - | expression tag |
| Val 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Leu 12 | - | expression tag |
| Ser 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Gly 15 | - | expression tag |
| Arg 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Pro 907 | Ser 907 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 337544.3 | |
| Branched | Number of molecules | 39 |
| Total formula weight | 27252.9 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5309.0 | |
| All* | Total formula weight | 370106.2 |
