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6BFL

Caspase-3 Mutant- D9A,D28A,T245D

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACaspase-3polymer17519671.31UniProt (P42574)
Pfam (PF00656)
In PDB
Homo sapiens (Human)CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
2BCaspase-3polymer10211924.61UniProt (P42574)
Pfam (PF00656)
In PDB
Homo sapiens (Human)CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
3CAC-ASP-GLU-VAL-ASP-CMKpolymer6534.91BIRD (PRD_000238)Homo sapiens
4AAZIDE IONnon-polymer42.01Chemie (AZI)
5waterwater18.0212Chemie (HOH)
Sequence modifications
A: 1 - 175 (UniProt: P42574)
PDBExternal DatabaseDetails
Ala 9Asp 9engineered mutation
Ala 28Asp 28engineered mutation
B: 176 - 277 (UniProt: P42574)
PDBExternal DatabaseDetails
Asp 245Thr 245engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight32130.9
Non-Polymers*Number of molecules1
Total formula weight42.0
All*Total formula weight32172.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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