6BFK
Caspase-3 Mutant- T245A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Caspase-3 | polymer | 175 | 19759.3 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 2 | B, D (C, D) | Caspase-3 | polymer | 103 | 12018.7 | 2 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 3 | E, F (F, E) | AC-ASP-GLU-VAL-ASP-CMK | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | Homo sapiens | |
| 4 | G, H, I, J, K (A, C, B, D) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 5 | L, M, N, O, P... (A, C, B, D, F...) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
C, D: 176 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 245 | Thr 245 | engineered mutation |
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 64626.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 114.9 | |
| All* | Total formula weight | 64741.0 |
