6BFJ
Caspase-3 Mutant - T245D,S249D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-3 | polymer | 175 | 19759.3 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 2 | B (B) | Caspase-3 | polymer | 103 | 12090.7 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 3 | C (C) | Ac-Asp-Glu-Val-Asp-CMK | polymer | 6 | 534.9 | 1 | BIRD (PRD_000238) | Homo sapiens | |
| 4 | D (A) | AZIDE ION | non-polymer | 42.0 | 1 | Chemie (AZI) | |||
| 5 | E, F, G (A, B, C) | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
B: 176 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Asp 245 | Thr 245 | engineered mutation |
| Asp 249 | Ser 249 | engineered mutation |
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32385.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 42.0 | |
| All* | Total formula weight | 32427.1 |
