6BEL
Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (T) | Template Strand | polymer | 16 | 4844.1 | 1 | Homo sapiens | ||
2 | B (P) | Primer Strand | polymer | 10 | 3069.0 | 1 | Homo sapiens | ||
3 | C (D) | Downstream Primer Strand | polymer | 5 | 1536.0 | 1 | Homo sapiens | ||
4 | D (A) | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (Human) | |
5 | E, G (T, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | F, H, I (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
7 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
8 | K (A) | 2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine | non-polymer | 483.2 | 1 | Chemie (F3C) | |||
9 | L (A) | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE | non-polymer | 307.2 | 1 | Chemie (DC) | |||
10 | M, N, O, P (T, P, D, A) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 47690.9 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 943.4 | |
All* | Total formula weight | 48634.3 |