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6BEL

Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(T)
Template Strandpolymer164844.11Homo sapiens
2B
(P)
Primer Strandpolymer103069.01Homo sapiens
3C
(D)
Downstream Primer Strandpolymer51536.01Homo sapiens
4D
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
5E, G
(T, A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6F, H, I
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
7J
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8K
(A)
2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidinenon-polymer483.21Chemie (F3C)
9L
(A)
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATEnon-polymer307.21Chemie (DC)
10M, N, O, P
(T, P, D, A)
waterwater18.0504Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47690.9
Non-Polymers*Number of molecules8
Total formula weight943.4
All*Total formula weight48634.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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