6BDV
Crystal structure of Caspase 3 S150A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-3 subunit p17 | polymer | 175 | 19743.3 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 2 | B (B) | Caspase-3 subunit p12 | polymer | 102 | 11910.6 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 3 | C (C) | Acetyl-Asp-Glu-Val-Asp-CMK | polymer | 6 | 534.9 | 1 | BIRD (PRD_000238) | synthetic construct | |
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F (A, B) | AZIDE ION | non-polymer | 42.0 | 2 | Chemie (AZI) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 1 - 175 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 150 | Ser 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32188.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 119.5 | |
| All* | Total formula weight | 32308.4 |
