6BCO

cryo-EM structure of TRPM4 in ATP bound state with short coiled coil at 2.9 angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D	Transient receptor potential cation channel subfamily M member 4	polymer	1254	140922.9	4	UniProt (Q7TN37) Pfam (PF18139) Pfam (PF00520) In PDB	Mus musculus (Mouse)	Calcium-activated non-selective cation channel 1,Long transient receptor potential channel 4,LTrpC4
2	B, A, C, D	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	4	Chemie (ATP)

Sequence modifications

B, A, C, D: 1 - 1213 (UniProt: Q7TN37)

PDB	External Database	Details
Arg 1214	-	expression tag
Asn 1215	-	expression tag
Ser 1216	-	expression tag
Lys 1217	-	expression tag
Ala 1218	-	expression tag
Tyr 1219	-	expression tag
Val 1220	-	expression tag
Asp 1221	-	expression tag
Glu 1222	-	expression tag
Leu 1223	-	expression tag
Thr 1224	-	expression tag
Ser 1225	-	expression tag
Arg 1226	-	expression tag
Gly 1227	-	expression tag
Arg 1228	-	expression tag
Leu 1229	-	expression tag
Glu 1230	-	expression tag
Val 1231	-	expression tag
Leu 1232	-	expression tag
Phe 1233	-	expression tag
Gln 1234	-	expression tag
Gly 1235	-	expression tag
Pro 1236	-	expression tag
Asp 1237	-	expression tag
Tyr 1238	-	expression tag
Lys 1239	-	expression tag
Asp 1240	-	expression tag
Asp 1241	-	expression tag
Asp 1242	-	expression tag
Asp 1243	-	expression tag
Lys 1244	-	expression tag
His 1245	-	expression tag
His 1246	-	expression tag
His 1247	-	expression tag
His 1248	-	expression tag
His 1249	-	expression tag
His 1250	-	expression tag
His 1251	-	expression tag
His 1252	-	expression tag
His 1253	-	expression tag
His 1254	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	563691.5
Non-Polymers*	Number of molecules	4
	Total formula weight	2028.7
All*	Total formula weight	565720.2

*Water molecules are not included.