6BCK
Crystal Structure of Broadly Neutralizing Antibody N49P7 in Complex with HIV-1 Clade AE strain 93TH057 gp120 core.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | clade A/E 93TH057 HIV-1 gp120 core | polymer | 353 | 39160.4 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (H) | N49P7 Fab heavy chain of N29P7 IgG | polymer | 228 | 24757.9 | 1 | Homo sapiens | ||
| 3 | C (L) | N49P7 Fab light chain from N49P7 IgG | polymer | 205 | 21763.1 | 1 | Homo sapiens | ||
| 4 | D, E, F, G, H... (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 11 | Chemie (NAG) | |||
| 5 | O, P (G, H) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 6 | Q, R, S (G, H, L) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
G: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85681.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2669.6 | |
| All* | Total formula weight | 88351.0 |
