6BB2
Lactate Dehydrogenase in complex with inhibitor (S)-5-((2-chlorophenyl)thio)-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | L-lactate dehydrogenase A chain | polymer | 331 | 36603.5 | 8 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | AA, CA, I, L, O... (G, H, A, B, C...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 3 | J, M, R, S, T... (A, B, D, F) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | DA, K, N, P, Z (H, A, B, C, F) | LACTIC ACID | non-polymer | 90.1 | 5 | Chemie (LAC) PubChem (61503) PubChem (107689) PubChem (612) | |||
| 5 | BA, U, W (G, D, E) | (2S)-5-[(2-chlorophenyl)sulfanyl]-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro[2,2'-bipyridin]-6(1H)-one | non-polymer | 525.0 | 3 | Chemie (D4J) PubChem (134821711) PubChem (134821712) | |||
| 6 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 596 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 292827.8 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 7909.2 | |
| All* | Total formula weight | 300737.0 |
