6B8Z
Multiconformer model of WT PTP1B with BB3 at 273 K
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37345.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (Human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | B (A) | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE | non-polymer | 741.4 | 1 | Chemie (FRJ) | |||
| 3 | C (A) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Ser 32 | Cys 32 | engineered mutation |
| Val 92 | Cys 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37345.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 741.4 | |
| All* | Total formula weight | 38087.0 |
