6B4I
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Nucleoporin GLE1 | polymer | 317 | 36375.1 | 2 | UniProt (Q53GS7) Pfam (PF07817) In PDB | Homo sapiens (Human) | hGLE1,GLE1-like protein |
2 | C, D | Nucleoporin like 2 | polymer | 50 | 5526.4 | 2 | UniProt (Q3B7J4) UniProt (by SIFTS) (O15504) In PDB | Homo sapiens (Human) | |
3 | E, F | ATP-dependent RNA helicase DDX19B | polymer | 430 | 48658.0 | 2 | UniProt (Q9UMR2) Pfam (PF00270) Pfam (PF00271) In PDB | Homo sapiens (Human) | DEAD box RNA helicase DEAD5,DEAD box protein 19B |
4 | B, A, E, F | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
5 | E, F | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence modifications
B, A: 383 - 698 (UniProt: Q53GS7)
C, D: 381 - 423 (UniProt: Q3B7J4)
E, F: 54 - 479 (UniProt: Q9UMR2)
PDB | External Database | Details |
---|---|---|
Met 382 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Gly 374 | - | expression tag |
Pro 375 | - | expression tag |
Ser 376 | - | expression tag |
Gly 377 | - | expression tag |
Ser 378 | - | expression tag |
Ile 379 | - | expression tag |
Ile 380 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 50 | - | expression tag |
Pro 51 | - | expression tag |
His 52 | - | expression tag |
Met 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 181119.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1424.2 | |
All* | Total formula weight | 182543.4 |