6B3B

AprA Methyltransferase 1 - GNAT in complex with Mn2+ , SAM, and Malonate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	AprA Methyltransferase 1	polymer	652	74825.8	1	UniProt (A0A1U7N2Z8) In PDB	Moorea bouillonii
2	A	S-ADENOSYLMETHIONINE	non-polymer		398.4	1	Chemie (SAM)
3	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
4	A	MALONATE ION	non-polymer		102.0	1	Chemie (MLI)
5	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6		water	water		18.0	447	Chemie (HOH)

Sequence modifications

A: 2 - 629 (UniProt: A0A1U7N2Z8)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Ala 1	-	expression tag
Ile 274	Ser 274	engineered mutation
Pro 528	Gln 528	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	74825.8
Non-Polymers*	Number of molecules	4
	Total formula weight	647.5
All*	Total formula weight	75473.4

*Water molecules are not included.