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6B2C

Macrophage Migration Inhibitory Factor in Complex with a Naphthyridinone Inhibitor (4b)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Macrophage migration inhibitory factorpolymer11412355.13UniProt (P14174)
Pfam (PF01187)
Homo sapiens (Human)MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
2D
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
3E
(B)
{2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-8-oxo-1,7-naphthyridin-7(8H)-yl}acetic acidnon-polymer381.31Chemie (C9Y)
4F, G, H
(A, B, C)
waterwater18.0143Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight37065.2
Non-Polymers*Number of molecules2
Total formula weight477.4
All*Total formula weight37542.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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