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6B1C

Macrophage Migration Inhibitory Factor in complex with a Naphthyridinone Inhibitor (4a)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Macrophage migration inhibitory factorpolymer11412355.13UniProt (P14174)
Pfam (PF01187)
Homo sapiens (Human)MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
2D, G, H, I
(A, C)
SULFATE IONnon-polymer96.14Chemie (SO4)
3E, F
(A, B)
2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-7-methyl-1,7-naphthyridin-8(7H)-onenon-polymer337.32Chemie (C9J)
4J, K, L
(A, B, C)
waterwater18.0144Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight37065.2
Non-Polymers*Number of molecules6
Total formula weight1058.9
All*Total formula weight38124.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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