6AYW
The structure of human CamKII with bound inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calcium/calmodulin-dependent protein kinase type II subunit delta | polymer | 302 | 34459.6 | 2 | UniProt (Q13557) Pfam (PF00069) | Homo sapiens (Human) | CaMK-II subunit delta |
| 2 | C, F (A, B) | N-[2-(dimethylamino)ethyl]-3-[6-(thiophen-2-yl)imidazo[1,2-b]pyridazin-3-yl]benzamide | non-polymer | 391.5 | 2 | Chemie (C2V) | |||
| 3 | D, E (A, B) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 2 | Chemie (DTT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 259 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 301 (UniProt: Q13557)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| His 1 | - | expression tag |
| Met 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68919.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1091.5 | |
| All* | Total formula weight | 70010.6 |
