6AVG

Crystal structure of the KFJ37 TCR-NY-ESO-1-HLA-B*07:02 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (H, A)	Beta-2-microglobulin	polymer	107	12519.0	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (Human)
2	B, F (C, B)	T-cell receptor alpha variable 4,TCR alpha chain	polymer	202	22532.1	2	UniProt (A0A0B4J268) Pfam (PF07686)	Homo sapiens (Human)
3	C, G (D, E)	T-cell receptor beta variable 9,TCR beta chain	polymer	245	27548.5	2	UniProt (A0A0B4J1U6) Pfam (PF07686)	Homo sapiens (Human)
4	D, H (G, F)	HLA class I histocompatibility antigen, B-7 alpha chain	polymer	362	40509.0	2	UniProt (P01889) Pfam (PF00129) Pfam (PF07654) Pfam (PF06623)	Homo sapiens (Human)	MHC class I antigen B*7
5	I, J (Q, P)	ALA-PRO-ARG-GLY-PRO-HIS-GLY-GLY-ALA-ALA-SER-GLY-LEU	polymer	13	1149.3	2	UniProt (by SIFTS) (P78358)	Homo sapiens
6	K, L, M, N, O... (H, C, D, G, A...)	water	water		18.0	504	Chemie (HOH)

Sequence modifications

C, B: 4 - 95 (UniProt: A0A0B4J268)

PDB	External Database	Details
Met 3	-	initiating methionine
Val 94	Gly 108	conflict

C, B: 96 - 204 (PDB: 6AVG)
D, E: 4 - 98 (UniProt: A0A0B4J1U6)

PDB	External Database	Details
Met 3	-	initiating methionine
Gln 51	His 67	conflict
Gly 98	Val 114	conflict

D, E: 99 - 247 (PDB: 6AVG)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	208515.6
All*	Total formula weight	208515.6

*Water molecules are not included.