6AUU
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-5-(trifluoromethyl)phenethyl)-4-methylpyridin-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric oxide synthase, brain | polymer | 422 | 48812.5 | 2 | UniProt (P29476) Pfam (PF02898) | Rattus norvegicus (Rat) | BNOS,Constitutive NOS,NC-NOS,NOS type I,Neuronal NOS,nNOS,Peptidyl-cysteine S-nitrosylase NOS1 |
| 2 | C, I (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, J (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 4 | E, K (A, B) | 6-(2-{3-[3-(dimethylamino)propyl]-5-(trifluoromethyl)phenyl}ethyl)-4-methylpyridin-2-amine | non-polymer | 365.4 | 2 | Chemie (BY7) | |||
| 5 | F, L (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | G, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | H (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 8 | M (B) | D-MANNITOL | non-polymer | 182.2 | 1 | Chemie (MTL) | |||
| 9 | O, P (A, B) | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97625.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2882.9 | |
| All* | Total formula weight | 100508.0 |
